Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974565 | 0.92 | DHFR (0.30) | DHFRTYMSXPO1 | |
| SCHEMBL6165169 | 0.90 | — | — | |
| SCHEMBL6160868 | 0.86 | LMNA (0.36) | TSHRRECQL | |
| SCHEMBL6160523 | 0.86 | GPR139 (0.32) | — | |
| SCHEMBL6161094 | 0.86 | LMNA (0.36) | TSHRRECQL | |
| SCHEMBL6160558 | 0.85 | — | — | |
| SCHEMBL6159284 | 0.84 | LMNA (0.35) | — | |
| SCHEMBL6967968 | 0.83 | — | — | |
| SCHEMBL6966214 | 0.83 | — | — | |
| SCHEMBL7078733 | 0.82 | HSP90B1 (0.32) | DHFRTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |