Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010485 | 0.94 | ALDH1A1 (0.50) | ALDH1A1NOX1PTPN1MAOB | |
| SCHEMBL8020571 | 0.93 | ALDH1A1 (0.51) | ALDH1A1NOX1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8010570 | 0.91 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APTPN1MAOB | |
| SCHEMBL8026762 | 0.91 | ALDH1A1 (0.47) | ALDH1A1NOX1PTPN1MAOB | |
| SCHEMBL8020417 | 0.90 | ALDH1A1 (0.46) | ALDH1A1PTPN1MAOB | |
| SCHEMBL8026201 | 0.89 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8021208 | 0.88 | ALDH1A1 (0.46) | ALDH1A1NOX1SMN1; SMN2NPC1HTT | |
| SCHEMBL8024218 | 0.88 | ALDH1A1 (0.44) | ALDH1A1PTPN1MAOB | |
| SCHEMBL8020187 | 0.87 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPTPTPN1 | |
| SCHEMBL8026970 | 0.85 | GPR132 (0.43) | ALDH1A1MEN1KMT2ARAB9APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | disclosed |