Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026720 | 0.88 | GABRB3 (0.40) | CYP3A4LMNAGABRB3GABRA2GABRB2 | |
| SCHEMBL8446583 | 0.81 | GABRB3 (0.41) | CYP3A4LMNAGABRB3GABRA2GABRB2 | |
| SCHEMBL7812035 | 0.79 | TDP1 (0.39) | TDP1CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL9028146 | 0.76 | GABRB3 (0.38) | CYP3A4LMNAGABRB3GABRA2GABRB2 | |
| SCHEMBL9028687 | 0.75 | GABRP (0.37) | CYP3A4LMNAGABRB3GABRA2GABRB2 | |
| SCHEMBL8822800 | 0.75 | GABRB3 (0.45) | CYP3A4LMNAGABRB3GABRA2GABRB2 | |
| SCHEMBL7825839 | 0.73 | TDP1 (0.41) | TDP1CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL8446016 | 0.70 | GABRA2 (0.41) | CYP3A4LMNAGABRB3GABRA2GABRB2 | |
| SCHEMBL3033497 | 0.69 | ALDH1A1 (0.59) | TDP1CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL8822967 | 0.68 | GABRA2 (0.40) | CYP3A4LMNAGABRB3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738713-B1 | Process for the preparation of pesticidal 1-(chloroaryl)heterocyclic compounds | RHONE POULENC AGROCHIMIE (FR) | 2000-02-09 | — | — | EP | disclosed |
| US-5726324-A | 1-(nitroaryl)pyrrole intermediates to pesticidal 1-(haloaryl)pyrroles | RHONE-POULENC INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5631381-A | Process for the preparation of pesticidal 1-(haloaryl) heterocyclic compounds | RHONE-POULENC INC. (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0738713-A1 | Process for the preparation of pesticidal 1-(haloaryl)heterocyclic compounds | RHONE-POULENC AGROCHIMIE (FR) | 1996-10-23 | — | — | EP | disclosed |