Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092300 | 1.00 | KMT2A (0.49) | KMT2ACASP1KDM4EL3MBTL1POLB | |
| SCHEMBL801406 | 0.86 | SMN1; SMN2 (0.50) | KMT2AKDM4EL3MBTL1TDP1NPC1 | |
| SCHEMBL31092297 | 0.86 | SMN1; SMN2 (0.50) | KMT2AKDM4EL3MBTL1TDP1NPC1 | |
| SCHEMBL8563215 | 0.81 | KMT2A (0.42) | KMT2AKDM4EL3MBTL1POLBCTDSP1 | |
| Nitrous Acid SCHEMBL29105413 | 0.81 | SMN1; SMN2 (0.45) | KMT2AKDM4EL3MBTL1TDP1NPC1 | |
| SCHEMBL29105412 | 0.80 | RAB9A (0.40) | KMT2AL3MBTL1POLBTDP1NPC1 | |
| SCHEMBL11723471 | 0.80 | TDP1 (0.41) | KMT2AKDM4EL3MBTL1POLBCTDSP1 | |
| SCHEMBL16563790 | 0.80 | ATR (0.49) | KMT2AKDM4EPOLBTDP1ALDH1A1 | |
| SCHEMBL14301697 | 0.78 | KMT2A (0.42) | KMT2ACASP1KDM4EL3MBTL1POLB | |
| SCHEMBL29105406 | 0.76 | NUDT1 (0.46) | KMT2ACASP1KDM4EL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650909-B | Synthesis method of 3-amino isonicotinic nitrile | 山西永津集团有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-115650909-A | Synthetic method of 3-amino isonicotinic nitrile | 山西永津集团有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115650909-B | Synthesis method of 3-amino isonicotinic nitrile | 山西永津集团有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115650909-B | Synthesis method of 3-amino isonicotinic nitrile | 山西永津集团有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115650909-A | Synthetic method of 3-amino isonicotinic nitrile | 山西永津集团有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115650909-A | Synthetic method of 3-amino isonicotinic nitrile | 山西永津集团有限公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-2366691-B1 | THE NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF | BEIJING YILING BIOENGINEERING CO LTD (CN) | 2015-04-15 | — | — | EP | disclosed |
| US-8940770-B2 | Nitropyridinyl ethyleneimine compound, the pharmaceutical composition containing it, the preparation method and use thereof | BEIJING YILING BIOENGINEERING CO., LTD. (CN) | 2015-01-27 | — | — | US | disclosed |
| US-8940770-B2 | Nitropyridinyl ethyleneimine compound, the pharmaceutical composition containing it, the preparation method and use thereof | BEIJING YILING BIOENGINEERING CO., LTD. (CN) | 2015-01-27 | — | — | US | disclosed |
| US-20140073796-A1 | NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF | BEIJING YILING BIOENGINEERING CO., LTD (CN) | 2014-03-13 | — | — | US | disclosed |
| US-20140073796-A1 | NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF | BEIJING YILING BIOENGINEERING CO., LTD (CN) | 2014-03-13 | — | — | US | disclosed |
| US-20120071515-A1 | NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF | BEIJING YILING BIOENGINEERING CO., LTD (CN) | 2012-03-22 | — | — | US | disclosed |
| EP-2366691-A1 | THE NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF | Beijing Yiling Bioengineering Co., Ltd. (CN) | 2011-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071515-A1 | NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF | ENPP1, DPYD, NME2 | KMT2A 2586/4885CASP1 1675/4885KDM4E 1856/4885 |
| US-20140073796-A1 | NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF | ENPP1, DPYD, NME2 | KMT2A 2586/4885CASP1 1675/4885KDM4E 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.