Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18525393 | 0.88 | ERN1 (0.46) | ERN1TNKS2PTPN1ACHETNKS | |
| SCHEMBL7520392 | 0.85 | ERN1 (0.57) | ERN1TNKS2PTPN1ACHETNKS | |
| SCHEMBL785414 | 0.83 | PDE4A (0.38) | ERN1TNKS2MAOAPTPN1ACHE | |
| SCHEMBL16024748 | 0.82 | ERN1 (0.50) | ERN1TNKS2PTPN1ACHETNKS | |
| SCHEMBL16024745 | 0.81 | ERN1 (0.46) | ERN1TNKS2PTPN1ACHETNKS | |
| SCHEMBL16015052 | 0.78 | ESR2 (0.47) | ERN1TNKS2PTPN1ACHEPTGS2 | |
| SCHEMBL16015010 | 0.77 | ACHE (0.48) | ERN1TNKS2PTPN1ACHETNKS | |
| SCHEMBL16014627 | 0.77 | ACHE (0.48) | ERN1TNKS2ACHETNKSGAA | |
| SCHEMBL18523531 | 0.77 | PTPN1 (0.44) | ERN1TNKS2PTPN1PTGS2KDM4E | |
| SCHEMBL16091526 | 0.77 | ACHE (0.59) | ERN1TNKS2PTPN1ACHETNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8747645-B2 | Process for preparing unsymmetrical biaryl alcohols | BASF SE (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20120067736-A1 | PROCESS FOR PREPARING UNSYMMETRICAL BIARYL ALCOHOLS | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
| WO-2010139687-A1 | METHOD FOR PREPARING UNSYMMETRICAL BIARYL ALCOHOLS | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |