Biotin

Biotin

SCHEMBL770769

CCCCC(N)C(=O)O.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.71
▸ MEN1 O00255 1/20 0.71
▸ ABL1 P00519 1/20 0.71
▸ LMNA P02545 1/20 0.71
▸ PKM P14618 1/20 0.71
▸ IDE P14735 1/20 0.71
▸ MAPK1 P28482 1/20 0.71
▸ KMT2A Q03164 1/20 0.71
▸ RIN1 Q13671 1/20 0.71
▸ L3MBTL1 Q9Y468 1/20 0.71
▸ HLCS P50747 6/20 0.61
▸ FOLH1 Q04609 2/20 0.47
▸ CA12 O43570 5/20 0.46
▸ CA1 P00915 5/20 0.46
▸ CA2 P00918 5/20 0.46
▸ CA9 Q16790 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL28084581 0.93 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9280317 0.93 TDP1 (0.61) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL27482647 0.92 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8011736 0.91 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8011738 0.91 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3790437 0.91 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL693036 0.91 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL28248497 0.89 TDP1 (0.61) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1033634 0.89 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8188769 0.88 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240050329-A1 METHODS FOR COSMETIC SKIN REMODELING ELC MAN LLC (US) 2024-02-15 — — US claimed
CN-111333664-A Biotin cross-linking agent, application and preparation method thereof 苏州昊帆生物股份有限公司 2020-06-26 — — CN claimed
WO-2002070702-A2 POLYPEPTIDES CAPABLE OF INTERACTING WITH SMAD POLYPEPTIDE CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-09-12 — — WO claimed
EP-1212414-A2 POLYPEPTIDES CAPABLE OF INTERACTING WITH THE SMAD PEPTIDE AND COMPRISING THE SEQUENCE PP(T/N)K IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-06-12 — — EP claimed
WO-2001014413-A2 POLYPEPTIDES CAPABLE OF INTERACTING WITH THE SMAD PEPTIDE AND COMPRISING THE SEQUENCE PP (T/N)K IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2001-03-01 — — WO claimed
EP-0222889-B1 CYTIDINE ANALOGS AMOCO CORP (US) 1993-10-27 — — EP claimed
EP-0222889-A4 CYTIDINE ANALOGS. INTEGRATED GENETICS INC (US) 1988-09-28 — — EP claimed
EP-0222889-A1 CYTIDINE ANALOGS. INTEGRATED GENETICS INC (US) 1987-05-27 — — EP claimed
WO-1986006726-A1 CYTIDINE ANALOGS INTEGRATED GENETICS, INC. (US) 1986-11-20 — — WO claimed
CN-119546632-A Cross-linked type V collagen assay 北欧生物科技公司 2025-02-28 — — CN disclosed
CN-118451106-A Combination therapy of Claudin 18.2 antagonists and PD-1/PD-L1 axis inhibitors 苏州创胜医药集团有限公司 2024-08-06 — — CN disclosed
CN-114630840-B Novel anti-CLDN 18.2 antibodies 苏州创胜医药集团有限公司 2024-08-02 — — CN disclosed
US-20240050329-A1 METHODS FOR COSMETIC SKIN REMODELING ELC MAN LLC (US) 2024-02-15 — — US disclosed
EP-4041185-A1 METHODS FOR COSMETIC SKIN REMODELING ELC Management LLC (US) 2022-08-17 — — EP disclosed
US-5405950-A N4 -substituted cytidines and process for incorporation into an oligonucleotides AMOCO CORPORATION (US) 1995-04-11 — — US disclosed
EP-0222889-B1 CYTIDINE ANALOGS AMOCO CORP (US) 1993-10-27 — — EP disclosed
US-5108893-A Oxidase, while produces peroxides an superoxide anions, reacting with substrate, chemiluminescent reagent and enhancer emitted light CANBERRA INDUSTRIES, INC. (US) 1992-04-28 — — US disclosed
EP-0222889-A4 CYTIDINE ANALOGS. INTEGRATED GENETICS INC (US) 1988-09-28 — — EP disclosed
EP-0222889-A1 CYTIDINE ANALOGS. INTEGRATED GENETICS INC (US) 1987-05-27 — — EP disclosed
WO-1986006726-A1 CYTIDINE ANALOGS INTEGRATED GENETICS, INC. (US) 1986-11-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240050329-A1 METHODS FOR COSMETIC SKIN REMODELING CUTA, PLOD3, KRT18 TDP1 612/4885MEN1 2593/4885ABL1 4735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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