SCHEMBL801233

SCHEMBL801233

CC(C)c1ccc(OCC(=O)O)cc1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.72
TSHR P16473 1/20 0.72
RAB9A P51151 2/20 0.59
ALOX15 P16050 1/20 0.59
NPC1 O15118 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
MAPT P10636 1/20 0.55
MAPK1 P28482 1/20 0.55
KMT2A Q03164 1/20 0.55
FKBP1A P62942 1/20 0.55
PTPN7 P35236 1/20 0.53
FFAR1 O14842 1/20 0.53
NR4A1 P22736 1/20 0.53
APEX1 P27695 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28601398 0.96 ALDH1A1 (0.68) ALDH1A1TSHRRAB9AALOX15NPC1
SCHEMBL9505445 0.95 ALDH1A1 (0.66) ALDH1A1TSHRRAB9AALOX15NPC1
SCHEMBL8302859 0.85 RAB9A (0.59) ALDH1A1TSHRRAB9ANPC1SMN1; SMN2
SCHEMBL12742272 0.84 ALDH1A1 (0.66) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL14032606 0.84 ALDH1A1 (0.66) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL5279314 0.84 ALDH1A1 (1.00) ALDH1A1TSHRRAB9AALOX15NPC1
SCHEMBL339492 0.83 ALOX15 (0.81) ALDH1A1TSHRALOX15SMN1; SMN2MAPT
SCHEMBL6717854 0.83 RAB9A (0.58) ALDH1A1TSHRRAB9ANPC1RXRA
SCHEMBL11011113 0.83 RAB9A (0.58) ALDH1A1TSHRRAB9ANPC1SMN1; SMN2
SCHEMBL1326182 0.83 RAB9A (0.58) ALDH1A1TSHRRAB9ANPC1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1971222-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2008-09-24 EP claimed
WO-2007059066-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2007-05-24 WO claimed
US-20070110844-A1 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. 2007-05-17 US claimed
EP-1054052-B1 Stabilized hydrotreated and hydrodewaxed lubricant compositions CIBA SC HOLDING AG (CH) 2006-06-28 EP claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-6410490-B1 OIL ADDITIVE MIXTURE CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-25 US claimed
EP-1054052-A2 Stabilized hydrotreated and hydrodewaxed lubricant compositions Ciba SC Holding AG (CH) 2000-11-22 EP claimed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP claimed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP claimed
CN-116284033-B Tubulin/AKT 1 double-targeting podophyllotoxin derivative and application thereof 常州大学 2025-02-25 CN disclosed
US-11932653-B2 Lycorine derivative, and pharmaceutical composition and use thereof SHANDONG DYNE MARINE BIOPHARMACEUTICAL CO., LTD (CN) 2024-03-19 US disclosed
EP-3470407-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2024-01-24 EP disclosed
CN-116284033-A tubulin/AKT 1 double-targeting podophyllotoxin derivative and application thereof 常州大学 2023-06-23 CN disclosed
CN-113201649-B Phenoxy carboxylic acid solid-phase extracting agent, and preparation method and application thereof 福建省长汀金龙稀土有限公司 2023-04-11 CN disclosed
EP-0700958-A1 Silica reinforced rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP disclosed
US-5045336-A Reducing sweet taste of high sugar foods, organic acids and acid salts AMSTAR SUGAR CORPORATION (US) 1991-09-03 US disclosed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP disclosed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP disclosed
US-4310512-A Derivatives of acetic and propionic acids, compositions containing same and use as malodor counteractants BUSH BOAKE ALLEN INC. (US) 1982-01-12 US disclosed
US-4013451-A 2-(SUBSTITUTED PHENOXY)PROPIONIC ACID PHILAGRO S.A. (FR) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11932653-B2 Lycorine derivative, and pharmaceutical composition and use thereof LCT, LARP7, LASP1 ALDH1A1 2939/4885TSHR 4386/4885RAB9A 883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.