Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24726549 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRCASP1MAPTKDM4E | |
| SCHEMBL15172767 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRCASP1MAPTKDM4E | |
| SCHEMBL1201436 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRCASP1MAPTKDM4E | |
| SCHEMBL1425839 | 0.77 | CYP3A4 (0.40) | ALDH1A1TSHRCASP1MAPTCYP3A4 | |
| SCHEMBL17339772 | 0.75 | TRPA1 (0.44) | ALDH1A1TSHRCASP1MAPTKDM4E | |
| SCHEMBL5812365 | 0.75 | POLB (0.44) | ALDH1A1TSHRCASP1MAPTKDM4E | |
| SCHEMBL12463870 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPTKDM4ETRPA1 | |
| SCHEMBL11589547 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP3A4TDP1MAPK1 | |
| SCHEMBL126200 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRCASP1MAPTKDM4E | |
| SCHEMBL3371394 | 0.75 | CD44 (0.44) | ALDH1A1TSHRCASP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6146429-A | DEVELOPER, COUPLER, BEESWAX AND PROTEIN HYDROLYZATES OR AMINO ACIDS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-11-14 | — | — | US | disclosed |