SCHEMBL1201436

SCHEMBL1201436

Cc1ccc(N)c(O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
TSHR P16473 5/20 0.42
CASP1 P29466 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 2/20 0.42
PKM P14618 1/20 0.41
CYP3A4 P08684 7/20 0.40
TDP1 Q9NUW8 6/20 0.40
TRPA1 O75762 1/20 0.40
MAPK1 P28482 1/20 0.39
ALOX15 P16050 3/20 0.38
THRB P10828 2/20 0.38
RECQL P46063 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.37
PDE10A Q9Y233 1/20 0.37
TP53 P04637 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11774960 0.82 ALOX15 (0.45) ALDH1A1TSHRCASP1MAPTKDM4E
SCHEMBL44351 0.82 ALDH1A1 (0.62) ALDH1A1TSHRCASP1MAPTKDM4E
SCHEMBL126200 0.81 ALDH1A1 (0.43) ALDH1A1TSHRCASP1MAPTKDM4E
SCHEMBL29631738 0.81 ALDH1A1 (0.43) ALDH1A1TSHRCASP1MAPTKDM4E
SCHEMBL2795922 0.81 ALDH1A1 (0.41) ALDH1A1TSHRCASP1MAPTKDM4E
SCHEMBL3371394 0.81 CD44 (0.44) ALDH1A1TSHRCASP1MAPTKDM4E
SCHEMBL30600212 0.81 ALDH1A1 (0.41) ALDH1A1TSHRCASP1MAPTKDM4E
Hydrochloric Acid SCHEMBL31026623 0.79 ALDH1A1 (0.42) ALDH1A1TSHRCASP1MAPTKDM4E
SCHEMBL11326454 0.79 ALDH1A1 (0.42) ALDH1A1TSHRCASP1MAPTKDM4E
Hydrochloric Acid SCHEMBL29285342 0.79 ALDH1A1 (0.42) ALDH1A1TSHRCASP1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116179084-A High-adhesion pavement marking paint and preparation process thereof 浙江兄弟路标涂料有限公司 2023-05-30 CN claimed
EP-3019141-B1 HARDENABLE DENTAL COMPOSITION CONTAINING A MIXTURE OF AGGLOMERATED AND AGGREGATED NANOPARTICLES, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2022-08-31 EP disclosed
WO-2018071920-A1 CURABLE URETHANE DIMETHACRYLATES AND DENTAL RESTORATIVE COMPOSITIONS THEREOF DM HEALTHCARE PRODUCTS, INC (US) 2018-04-19 WO disclosed
US-9782329-B2 Hardenable dental composition containing a mixture of agglomerated and aggregated nano-particles, kit of parts and use thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2017-10-10 US disclosed
US-20160136059-A1 HARDENABLE DENTAL COMPOSITION CONTAINING A MIXTURE OF AGGLOMERATED AND AGGREGATED NANO-PARTICLES, KIT OF PARTS AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2016-05-19 US disclosed
EP-3019141-A1 HARDENABLE DENTAL COMPOSITION CONTAINING A MIXTURE OF AGGLOMERATED AND AGGREGATED NANO-PARTICLES, KIT OF PARTS AND USE THEREOF 3M Innovative Properties Company (US) 2016-05-18 EP disclosed
US-20150141619-A1 CROSS-LINKED COLLAGEN COMPRISING METALLIC ANTICANCER AGENTS MIMEDX GROUP, INC. 2015-05-21 US disclosed
US-20150141619-A1 CROSS-LINKED COLLAGEN COMPRISING METALLIC ANTICANCER AGENTS MIMEDX GROUP, INC. 2015-05-21 US disclosed
WO-2015006087-A1 HARDENABLE DENTAL COMPOSITION CONTAINING A MIXTURE OF AGGLOMERATED AND AGGREGATED NANO-PARTICLES, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-01-15 WO disclosed
CN-101516896-B Phosphate ester compound, metal salt thereof, dental material, and demtal composition MITSU CHEMICALS INC 2013-06-05 CN disclosed
US-6306926-B1 POLYMER COMPOSITION WITH CATION ACTIVE MATERIAL 3M INNOVATIVE PROPERTIES COMPANY 2001-10-23 US disclosed
EP-1083859-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2001-03-21 EP disclosed
US-6187836-B1 DENTISTRY; PHOTOPOLYMERIZATION 3M INNOVATIVE PROPERTIES COMPANY 2001-02-13 US disclosed
EP-0630641-B1 Method and dispenser for making dental products DENTSPLY INT INC (US) 2000-10-11 EP disclosed
WO-1999062460-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-12-09 WO disclosed
US-5614596-A POLYMETALLOOXANES REGENTS OF UNIVERSITY OF MICHIGAN (US) 1997-03-25 US disclosed
US-5554665-A PHOTO OR THERMAL ACRYLIC POLYMERIZATION DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) 1996-09-10 US disclosed
US-5444104-A Dental restorative material based on a polycarbonate dimethacrylate JENERIC/PENTRON, INC. (US) 1995-08-22 US disclosed
EP-0630641-A1 Method and dispenser for making dental products DENTSPLY INTERNATIONAL, INC. (US) 1994-12-28 EP disclosed
US-5276068-A Dimethacrylate compounds containing carbonate groups, adhesives, restoration material JENERIC/PENTRON, INC. (US) 1994-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160136059-A1 HARDENABLE DENTAL COMPOSITION CONTAINING A MIXTURE OF AGGLOMERATED AND AGGREGATED NANO-PARTICLES, KIT OF PARTS AND USE THEREOF NOX3, ILK, NOX1 ALDH1A1 368/4885TSHR 3641/4885CASP1 898/4885
US-20150141619-A1 CROSS-LINKED COLLAGEN COMPRISING METALLIC ANTICANCER AGENTS COL2A1, COL1A1, COL14A1 ALDH1A1 2144/4885TSHR 3571/4885CASP1 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.