Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15375590 | 0.87 | FABP4 (0.54) | FABP4FABP5LMNAPTGDR2SMN1; SMN2 | |
| SCHEMBL2236821 | 0.86 | FABP4 (0.46) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL8014177 | 0.85 | RXRA (0.51) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL15375447 | 0.83 | FABP4 (0.57) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL1539411 | 0.80 | CDK4 (0.42) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL9051241 | 0.80 | RXRA (0.46) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL8305675 | 0.80 | TDP1 (0.47) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL15375470 | 0.78 | RXRA (0.45) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL28038053 | 0.78 | RXRA (0.45) | FABP4FABP5RXRARXRBRXRG | |
| SCHEMBL9445841 | 0.77 | LMNA (0.45) | FABP4FABP5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9095462-A | — | — | None | — | — | JP | disclosed |
| JP-H0995462-A | PRODUCTION OF ALPHA-HYDROXYPHENYLACETIC ACID DERIVATIVE | SHIONOGI & CO LTD | 1997-04-08 | — | — | JP | disclosed |