⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014534 | 0.78 | — | — | |
| SCHEMBL6628245 | 0.76 | — | — | |
| SCHEMBL18607993 | 0.74 | HSD11B1 (0.36) | — | |
| SCHEMBL4034937 | 0.74 | AGL (0.36) | — | |
| SCHEMBL1359811 | 0.74 | — | — | |
| SCHEMBL24307669 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL27675556 | 0.73 | GBA1 (0.43) | — | |
| SCHEMBL1219882 | 0.73 | — | — | |
| SCHEMBL17143175 | 0.73 | ALOX15 (0.33) | — | |
| SCHEMBL3259704 | 0.73 | LTA4H (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666265-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5527786-A | ANTIDIABETIC AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0666265-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-08-09 | — | — | EP | disclosed |