Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 12/20 | 1.00 |
| ▸ | AR | P10275 | 12/20 | 1.00 |
| ▸ | NR3C2 | P08235 | 11/20 | 1.00 |
| ▸ | ESR1 | P03372 | 10/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 10/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648377 | 0.86 | PGR (1.00) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL4181272 | 0.85 | NR3C1 (0.79) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL8146749 | 0.85 | PGR (0.82) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL6650996 | 0.84 | PGR (1.00) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL7092892 | 0.84 | PGR (1.00) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL6650300 | 0.83 | PGR (1.00) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL6648200 | 0.83 | PGR (1.00) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL12899044 | 0.82 | PGR (0.87) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL7954577 | 0.80 | PGR (1.00) | PGRNR3C1ARNR3C2ESR1 | |
| SCHEMBL8871001 | 0.79 | PGR (0.79) | PGRNR3C1ARNR3C2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121450-A | NON-STEROIDAL COMPOUNDS WHICH ARE HIGH AFFINITY, HIGH SELECTIVITY MODULATORS FOR STEROID RECEPTORS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2000-09-19 | — | — | US | disclosed |