Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 7/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014329 | 0.90 | MEN1 (0.51) | GAAHMGCRMEN1KMT2ANPSR1 | |
| SCHEMBL8011719 | 0.82 | HMGCR (0.51) | GAAHMGCRMEN1KMT2ANPSR1 | |
| SCHEMBL8003353 | 0.81 | HMGCR (0.47) | GAAHMGCRMEN1KMT2ANPSR1 | |
| SCHEMBL8766613 | 0.76 | HMGCR (0.49) | GAAHMGCRMEN1KMT2ANPSR1 | |
| SCHEMBL8766586 | 0.75 | MEN1 (0.43) | GAAHMGCRMEN1KMT2AIDH1 | |
| SCHEMBL5363346 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7119145 | 0.74 | HMGCR (0.46) | GAAHMGCRMEN1KMT2ANPSR1 | |
| SCHEMBL8973534 | 0.71 | CA12 (0.56) | HMGCRMAPT | |
| SCHEMBL3891522 | 0.71 | GAA (0.67) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7117955 | 0.71 | GAA (0.43) | GAAHMGCRMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835116-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1998-04-15 | — | — | EP | claimed |
| WO-1997002037-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1997-01-23 | — | — | WO | claimed |
| US-6060464-A | Compounds and pharmaceutical compositions containing them | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-09 | — | — | US | disclosed |
| EP-0835116-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997002037-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1997-01-23 | — | — | WO | disclosed |