Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 10/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331154 | 0.90 | RXRA (0.47) | RARARARBRARGPPARGRXRA | |
| SCHEMBL8016184 | 0.85 | RXRA (0.42) | RARARARBRARGPPARGRXRA | |
| SCHEMBL6756017 | 0.82 | RARA (0.48) | RARARARBRARGPPARGRXRA | |
| SCHEMBL8025898 | 0.81 | RARA (0.46) | RARARARBRARGPPARGRXRA | |
| SCHEMBL8331635 | 0.81 | PDK2 (0.46) | RARARARBRARGRXRAPDK2 | |
| SCHEMBL6240892 | 0.81 | ACHE (0.43) | RARARARBRARGPDK2HPGD | |
| SCHEMBL6240887 | 0.81 | ACHE (0.43) | RARARARBRARGPDK2HPGD | |
| SCHEMBL8331156 | 0.80 | PDK2 (0.37) | RARARARBRARGPPARGRXRA | |
| SCHEMBL6810772 | 0.79 | RARA (0.49) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6752848 | 0.79 | RARA (0.46) | RARARARBRARGPPARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |