Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 8/20 | 0.46 |
| ▸ | RARB | P10826 | 7/20 | 0.46 |
| ▸ | RARG | P13631 | 4/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756017 | 0.87 | RARA (0.48) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8015897 | 0.87 | RARA (0.61) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6752848 | 0.85 | RARA (0.46) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8016189 | 0.81 | RARA (0.43) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8025897 | 0.81 | RXRA (0.43) | RARARARBRARGRXRACA12 | |
| SCHEMBL6086727 | 0.80 | RAB9A (0.42) | PDK2MAPK1HPGDNPC1MAPT | |
| SCHEMBL8018376 | 0.79 | RARA (0.54) | RARARARBRARGRXRACA12 | |
| SCHEMBL10846840 | 0.79 | RARA (0.72) | RARARARBRARGRXRACA12 | |
| SCHEMBL10846838 | 0.79 | RARA (0.72) | RARARARBRARGRXRACA12 | |
| SCHEMBL6085623 | 0.78 | RXRA (0.50) | RARARARBRARGRXRACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059861-A1 | SELECTIVE RETINOIC ACID ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |