Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 18/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12986494 | 0.90 | NPC1 (0.39) | — | |
| SCHEMBL20292039 | 0.72 | DDB1 (0.46) | PLATGABRA1GABRB2HTR2C | |
| SCHEMBL27934920 | 0.71 | NPC1 (0.38) | PLAT | |
| Hydrochloric Acid SCHEMBL28112386 | 0.70 | GABRA1 (0.45) | PLATGABRA1GABRB2HTR2C | |
| Hydrochloric Acid SCHEMBL31510718 | 0.70 | DDB1 (0.45) | PLATGABRA1GABRB2HTR2C | |
| SCHEMBL8007356 | 0.70 | NPC1 (0.41) | PLATGABRA1GABRB2 | |
| SCHEMBL8017401 | 0.69 | PLAT (0.41) | PLAT | |
| SCHEMBL29945922 | 0.68 | SLC6A2 (0.48) | PLAT | |
| SCHEMBL29945848 | 0.68 | HTR6 (0.46) | — | |
| SCHEMBL28901178 | 0.68 | PLAU (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037074-A1 | MUTILIN 14-ESTER DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2000-06-29 | — | — | WO | disclosed |