Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945922 | 0.87 | SLC6A2 (0.48) | HTR6SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL29946087 | 0.85 | CYP19A1 (0.39) | HTR6SLC6A2SLC6A4SLC6A3PRMT5 | |
| SCHEMBL29946103 | 0.81 | SLC6A2 (0.39) | HTR6SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL29946020 | 0.75 | MEN1 (0.48) | SMN1; SMN2PRMT5ALDH1A1KMT2A | |
| SCHEMBL29946017 | 0.75 | MEN1 (0.48) | SMN1; SMN2PRMT5ALDH1A1KMT2A | |
| SCHEMBL29946162 | 0.73 | HTR6 (0.49) | HTR6SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL23410958 | 0.72 | HTR3A (0.42) | NPC1RAB9ASMN1; SMN2HTR3AALDH1A1 | |
| SCHEMBL29945896 | 0.70 | HTR6 (0.37) | HTR6SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL29976024 | 0.69 | HTR6 (0.51) | HTR6SLC6A2SLC6A4SLC6A3PRMT5 | |
| SCHEMBL8017108 | 0.68 | PLAT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |