Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626592 | 0.86 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7767567 | 0.77 | TRPA1 (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8018392 | 0.73 | SLC5A1 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL28250606 | 0.71 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2MAPK1HPGD | |
| SCHEMBL24419694 | 0.69 | TRPA1 (0.59) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL26036295 | 0.69 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL30500513 | 0.68 | NPC1 (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL26036292 | 0.68 | LMNA (0.44) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL444673 | 0.67 | TRPA1 (0.48) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL394746 | 0.66 | ALDH1A1 (0.48) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983240-A1 | LIGHT-STABILIZED ORGANIC POLYMERS | Great Lakes Chemical (Europe) GmbH (CH) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998050360-A1 | LIGHT-STABILIZED ORGANIC POLYMERS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1998-11-12 | — | — | WO | disclosed |