Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019561 | 0.76 | CYP3A4 (0.42) | ALOX15KDM4CPDK1PDK2PDK3 | |
| SCHEMBL8018561 | 0.74 | AR (0.47) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL8016868 | 0.74 | AR (0.52) | AR | |
| SCHEMBL8006388 | 0.72 | RAF1 (0.44) | PDK1PDK2PDK3PDK4RIPK1 | |
| SCHEMBL1192098 | 0.70 | RIPK1 (0.49) | ALOX15KDM4CRIPK1HTR2ASLC6A4 | |
| SCHEMBL22957883 | 0.70 | RIPK1 (0.62) | MEN1KMT2AALOX15KDM4CRIPK1 | |
| SCHEMBL896642 | 0.70 | ALDH1A1 (0.52) | ARMEN1KMT2ACHEK1KCNQ3 | |
| SCHEMBL30136739 | 0.70 | ALDH1A1 (0.52) | ARMEN1KMT2ACHEK1KCNQ3 | |
| SCHEMBL8026319 | 0.69 | GAA (0.51) | MEN1KMT2APKM | |
| SCHEMBL30171207 | 0.68 | AR (1.00) | ARKCNQ3KCNQ2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097998-A1 | ARYLCHALCOGENO-ARYLALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |