Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146444 | 0.86 | SLC6A2 (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8961286 | 0.86 | SLC6A2 (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10479865 | 0.84 | SLC6A2 (0.41) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10479867 | 0.84 | SLC6A2 (0.41) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9809556 | 0.83 | MAOB (0.40) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8857752 | 0.82 | PROKR1 (0.37) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4798580 | 0.82 | SLC6A2 (0.40) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4798556 | 0.82 | SLC6A2 (0.40) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4798573 | 0.82 | SLC6A2 (0.40) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8771449 | 0.82 | SLC6A2 (0.40) | MAOBMAOASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013198-A | LIQUID CRYSTALLINE COMPOUNDS MODIFIED TO HAVE A TRIFLUOROMETHYLPHENYL GROUP OR TRIFLUOROMETHOXYPHENYL GROUP AS EXAMPLE OF KNOWN TERMINAL SUBSTITUENT; CHEMICAL STABILITY, HIGH VOLTAGE HOLDING RATIO, GOOD UV STABILITY | CHISSO CORPORATION (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0761799-A1 | Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device | Chisso Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |