SCHEMBL7755535

SCHEMBL7755535

Nc1cc(OS(=O)(=O)O)cc([N+](=O)[O-])c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.59
GAA P10253 1/20 0.59
PLCG1 P19174 1/20 0.59
DNMT1 P26358 1/20 0.59
CASP6 P55212 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
GPR35 Q9HC97 6/20 0.56
CA9 Q16790 6/20 0.55
CA12 O43570 5/20 0.55
CA1 P00915 5/20 0.55
CA2 P00918 5/20 0.55
CA4 P22748 1/20 0.49
ALDH1A1 P00352 5/20 0.41
HPGD P15428 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 1/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9351734 0.87 CA9 (0.59) NSD2GAAPLCG1DNMT1CASP6
SCHEMBL11290098 0.81 ALDH1A1 (0.51) NSD2GAAPLCG1DNMT1CASP6
SCHEMBL177115 0.75 CASP6 (1.00) NSD2GAAPLCG1DNMT1CASP6
SCHEMBL8020759 0.74 CISD1 (0.41) NSD2GAAPLCG1DNMT1CASP6
Water SCHEMBL4800321 0.73 CASP6 (0.97) NSD2GAAPLCG1DNMT1CASP6
SCHEMBL9310524 0.73 GPR35 (0.69) NSD2GAAPLCG1DNMT1CASP6
SCHEMBL6330272 0.73 ALDH1A1 (0.65) NSD2GAAPLCG1DNMT1CASP6
SCHEMBL27650626 0.73 CASP6 (0.74) NSD2GAAPLCG1DNMT1CASP6
SCHEMBL10709141 0.73 KDM4E (0.48) GAAGPR35CA1CA2ALDH1A1
SCHEMBL8018809 0.73 CISD1 (0.40) GAACA9CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669380-B1 Process for the preparation of azo dyes CIBA SC HOLDING AG (CH) 2001-03-28 EP disclosed
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0669380-A2 Process for the preparation of azo dyes CIBA-GEIGY AG (CH) 1995-08-30 EP disclosed
EP-0648816-A1 Dyeing of leather with dyestuff mixtures CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0061670-B2 Process for dyeing leather and pelts with dye mixtures CIBA GEIGY AG (CH) 1994-06-01 EP disclosed
EP-0231147-B1 PROCESS FOR THE TRICHROMATIC DYEING OF LEATHER CIBA-GEIGY AG (CH) 1992-01-15 EP disclosed
EP-0181836-B1 PROCESS FOR IMPROVING THE LIGHT FASTNESS OF DYED LEATHERS CIBA-GEIGY AG (CH) 1988-12-21 EP disclosed
EP-0148120-B1 ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-11-23 EP disclosed
EP-0148121-B1 ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
EP-0150676-B1 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-10-12 EP disclosed
EP-0079858-A1 Azo dyestuffs, metal complexes thereof, their preparation and use CIBA-GEIGY AG (CH) 1983-05-25 EP disclosed
EP-0019851-B1 1:2 CHROMIUM COMPLEX DYESTUFFS OF THE AZOMETHINE AND/OR AZO SERIES, THEIR PREPARATION AND USE IN DYEING AND PRINTING POLYAMIDE OR CELLULOSE MATERIALS CIBA-GEIGY AG (CH) 1983-05-11 EP disclosed
EP-0061670-A1 Process for dyeing leather and pelts with dye mixtures CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed
EP-0009466-B1 1 : 2-BIS-CHROMIUM-COMPLEX DYESTUFFS FROM POLYAZO- OR DISAZO-AZOMETHINE COMPOUNDS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1982-05-19 EP disclosed
EP-0048693-A2 Disazo dyestuffs, metal complexes thereof, their preparation and use CIBA-GEIGY AG (CH) 1982-03-31 EP disclosed
EP-0005207-B1 BIS-1:2 CHROME-DISAZO-BISAZO METHINE DYESTUFFS, THEIR PREPARATION AND USE FOR DYEING OF LEATHER CIBA-GEIGY AG (CH) 1981-12-09 EP disclosed
EP-0027950-A2 Fibre-reactive chromium complex dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1981-05-06 EP disclosed
EP-0019851-A1 1:2 Chromium complex dyestuffs of the azomethine and/or azo series, their preparation and use in dyeing and printing polyamide or cellulose materials CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed
EP-0009466-A1 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use CIBA-GEIGY AG (CH) 1980-04-02 EP disclosed
EP-0005207-A2 Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather CIBA-GEIGY AG (CH) 1979-11-14 EP disclosed