Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786690 | 0.88 | HTT (0.57) | MEN1KMT2AALDH1A1PKMPOLB | |
| SCHEMBL11780795 | 0.84 | MKNK1 (0.42) | ALDH1A1ESR1ESR2SMN1; SMN2HTT | |
| SCHEMBL11783952 | 0.84 | HCAR1 (0.43) | MEN1KMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL11786697 | 0.83 | FGFR1 (0.43) | KMT2AALDH1A1SMN1; SMN2MAPTFGFR1 | |
| SCHEMBL11780228 | 0.78 | SMN1; SMN2 (0.48) | MEN1KMT2AESR1ESR2SMN1; SMN2 | |
| SCHEMBL9765862 | 0.75 | KDM4E (0.44) | MEN1KMT2AALDH1A1PKMGAA | |
| SCHEMBL9343492 | 0.74 | KDM5B (0.38) | ALDH1A1PKMKCNQ3KCNQ2HTT | |
| SCHEMBL11785278 | 0.74 | HCAR1 (0.53) | MEN1KMT2AALDH1A1PKMPOLB | |
| SCHEMBL11788419 | 0.73 | PKM (0.45) | PKMGAASMN1; SMN2 | |
| SCHEMBL9723106 | 0.73 | GABRA2 (0.40) | MEN1KMT2ALMNAKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100257-A | 2-HALOALKYL,3-(HALOALKYL, ALKENYL, OR ALKYNYL),5-(SUBSTITUTED PHENYL OR HETEROCYCLE),6-ALKYL-PYRIMIDIN-4-ONE COMPOUNDS OF GIVEN STRUCTURE; USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-3981715-A | 2,3,5-Substituted-6-trifluoromethyl-1,3-diazin-4-ones herbicides | AMERICAN CYANAMID COMPANY (US) | 1976-09-21 | — | — | US | disclosed |