Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765831 | 0.90 | KDM4E (0.41) | KDM4EMAPTSMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL8018827 | 0.75 | MEN1 (0.45) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL9765814 | 0.74 | ALDH1A1 (0.49) | MAPTSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9765875 | 0.74 | ALDH1A1 (0.36) | KDM4EMAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11786690 | 0.73 | HTT (0.57) | MAPTSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11783952 | 0.73 | HCAR1 (0.43) | SMN1; SMN2KMT2ALMNAGAACYP3A4 | |
| SCHEMBL9343492 | 0.73 | KDM5B (0.38) | ALDH1A1LMNAPKM | |
| SCHEMBL11780795 | 0.73 | MKNK1 (0.42) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9341586 | 0.72 | KDM5B (0.37) | ALDH1A1ABL1LMNAPKM | |
| SCHEMBL9723106 | 0.72 | GABRA2 (0.40) | L3MBTL1KMT2ALMNAACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990512-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0357201-A2 | Pyridyl pyrimidinone derivatives with an insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-07 | — | — | EP | disclosed |