SCHEMBL8019089

SCHEMBL8019089

C=Cc1ccc(CSC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.39
HDAC8 Q9BY41 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNA4 P43681 1/20 0.38
MAPT P10636 4/20 0.36
TP53 P04637 4/20 0.36
TDP1 Q9NUW8 2/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
XDH P47989 1/20 0.34
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8431662 0.81 ALDH1A1 (0.55) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL5066949 0.81 ALDH1A1 (0.55) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL5209430 0.80 MAPT (0.44) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL5072084 0.78 ALDH1A1 (0.46) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL13074628 0.78 ALDH1A1 (0.46) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL24691363 0.77 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL6389194 0.77 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL7714658 0.77 ALDH1A1 (0.52) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL10746889 0.77 ALDH1A1 (0.44) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL9580112 0.77 ALDH1A1 (0.44) ALDH1A1TSHRHDAC8CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024042159-A1 CONDUCTIVE PRESSURE SENSITIVE ADHESIVE HENKEL AG & CO. KGAA (DE) 2024-02-29 WO disclosed
EP-3501482-A1 TWO-PACKAGE DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2019-06-26 EP disclosed
US-20110230420-A1 RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS ENZON PHARMACEUTICALS, INC. (US) 2011-09-22 US disclosed
US-20080038669-A1 NON-TRULY-SPHERICAL HIGH-MOLECULAR FINE PARTICLES, PROCESS FOR PRODUCING THE SAME, INKJET INK COMPOSITION CONTAINING FINE PARTICLES, LITHOGRAPHIC PRINTING PLATE USING THE SAME, PROCESS FOR PRODUCING PRINTING PLATE, AND ELECTROPHORETIC PARTICLES-CONTAINING COMPOSITION CONTAINING FINE PARTICLES FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
EP-0762197-B1 Photographic recording material AGFA GEVAERT AG (DE) 2000-01-12 EP disclosed
US-5888719-A CONTINING A POLYMER; DARK DECAY STABILITY AGFA-GEVAERT AG (DE) 1999-03-30 US disclosed
US-5674668-A Photographic recording material AGFA-GEVAERT (DE) 1997-10-07 US disclosed
EP-0762197-A1 Photographic recording material Agfa-Gevaert AG (DE) 1997-03-12 EP disclosed
US-5518877-A POLYPEPTIDE-ADDITION POLYMER AGFA-GEVAERT AG (DE) 1996-05-21 US disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230420-A1 RELEASABLE CONJUGATES FOR NUCLEIC ACIDS DELIVERY SYSTEMS PHAX, KPNA6, KPNA2 ALDH1A1 3693/4885TSHR 2363/4885HDAC8 715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.