SCHEMBL8019452

SCHEMBL8019452

O=P(Oc1ccc(O)c(O)c1O)(Oc1ccc(O)c(O)c1O)Oc1ccc(O)c(O)c1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 4/20 0.37
INPP5A Q14642 4/20 0.37
AKT1 P31749 1/20 0.37
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37
HIF1A Q16665 1/20 0.35
EPAS1 Q99814 1/20 0.35
DBH P09172 1/20 0.33
CYP3A4 P08684 2/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
HPGD P15428 2/20 0.32
ALOX15 P16050 2/20 0.32
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3093492 0.84 INPPL1 (0.56) INPPL1INPP5AAKT1SELLSELP
SCHEMBL28746864 0.75 INPPL1 (0.37) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL30595265 0.72 SRC (0.47) CYP3A4ALDH1A1LMNAHPGDALOX15
SCHEMBL2549908 0.72 IDO1 (0.52) ALOX15HSD17B10MAPTGAA
SCHEMBL29640371 0.72 HIF1A (0.41) SELLSELPHIF1AEPAS1DBH
SCHEMBL1685758 0.70 GAA (0.53) INPPL1INPP5AHIF1ACYP3A4ALDH1A1
SCHEMBL9742294 0.69 KDM4E (0.65) HIF1AEPAS1CYP3A4ALDH1A1LMNA
SCHEMBL2160829 0.68 SELL (0.37) SELLSELPHIF1AEPAS1DBH
SCHEMBL338346 0.67 ALDH1A1 (0.57) SELLSELPHIF1ADBHCYP3A4
SCHEMBL29373601 0.67 ALDH1A1 (0.57) SELLSELPHIF1ADBHCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1022312-A1 Flame-retardant thermoplastic resin composition Techno Polymer Co., Ltd. (JP) 2000-07-26 EP claimed
US-6071992-A FOR MOLDED PRODUCTS TECHNO POLYMER CO., LTD. (JP) 2000-06-06 US claimed
EP-1022312-A1 Flame-retardant thermoplastic resin composition Techno Polymer Co., Ltd. (JP) 2000-07-26 EP disclosed
US-6071992-A FOR MOLDED PRODUCTS TECHNO POLYMER CO., LTD. (JP) 2000-06-06 US disclosed