Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 6/20 | 0.35 |
| ▸ | MMP3 | P08254 | 6/20 | 0.35 |
| ▸ | MMP9 | P14780 | 5/20 | 0.35 |
| ▸ | MMP1 | P03956 | 5/20 | 0.35 |
| ▸ | MMP13 | P45452 | 5/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945464 | 0.79 | PLA2G7 (0.49) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL7040815 | 0.77 | PLA2G7 (0.50) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL7518193 | 0.77 | PLA2G7 (0.50) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL12692931 | 0.75 | PLA2G7 (0.49) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL422413 | 0.75 | PLA2G7 (0.49) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL419379 | 0.74 | F2 (0.48) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL7968322 | 0.73 | PLA2G7 (0.47) | PLA2G7NR1H2NR1H3 | |
| SCHEMBL20976949 | 0.72 | PLA2G7 (0.46) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL12600734 | 0.72 | PLA2G7 (0.46) | PLA2G7MMP2MMP3MMP9MMP1 | |
| SCHEMBL5036973 | 0.72 | PLA2G7 (0.46) | PLA2G7MMP2MMP3MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | MMP3, MMP7, MMP9 | PLA2G7 93/4885MMP2 5/4885MMP3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.