SCHEMBL8020107

SCHEMBL8020107

Cc1ccc(C(C)C)c(OP(=S)(OCl)Oc2cc(C)ccc2C(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 2/20 0.41
TRPA1 O75762 1/20 0.41
CHRM1 P11229 1/20 0.41
SLC6A2 P23975 1/20 0.41
ADRA1A P35348 1/20 0.41
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003274 0.84 L3MBTL1 (0.42) L3MBTL1MAPTLMNATRPA1CHRM1
SCHEMBL8020105 0.83 L3MBTL1 (0.46) L3MBTL1MAPTLMNATRPA1CHRM1
SCHEMBL8148726 0.83 L3MBTL1 (0.46) L3MBTL1MAPTLMNATRPA1CHRM1
SCHEMBL9003266 0.81 L3MBTL1 (0.47) L3MBTL1MAPTLMNATRPA1CHRM1
SCHEMBL8016128 0.78 P2RX3 (0.36) L3MBTL1LMNASLC6A2HTR2B
SCHEMBL8023873 0.76 HPGD (0.37) L3MBTL1MAPTLMNA
SCHEMBL8652331 0.75 L3MBTL1 (0.45) L3MBTL1MAPTLMNA
SCHEMBL8731929 0.73 LMNA (0.47) L3MBTL1MAPTLMNATRPA1CHRM1
SCHEMBL9463062 0.73 LMNA (0.54) L3MBTL1LMNATRPA1CHRM1SLC6A2
SCHEMBL11043528 0.73 LMNA (0.54) L3MBTL1LMNATRPA1CHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573182-B1 Process for extracting metal values AVECIA LTD (GB) 2000-01-05 EP disclosed
US-5728853-A AMIDO(BISTHIOPHOSHORYL) COMPOUNDS USEFUL FOR EXTRACTING METAL VALUES FROM AQUEOUS SOLUTIONS OF METAL SALTS ZENECA LIMITED (GB) 1998-03-17 US disclosed
US-5557003-A SOLVENT EXTRACTION OF ZINC FROM ORE ZENECA LIMITED (GB) 1996-09-17 US disclosed
US-5502250-A HYDROMETALLURGICAL PROCESS FOR EXTRACTING ZINC FROM ORE ZENECA LIMITED (GB) 1996-03-26 US disclosed
US-5433855-A Solvent extraction ZENECA LIMITED (GB) 1995-07-18 US disclosed
US-5393431-A Solvent extraction using a aminobis(thiophosphoryl) compound ZENECA LIMITED (GB) 1995-02-28 US disclosed
EP-0573182-A1 Process for extracting metal values ZENECA LIMITED (GB) 1993-12-08 EP disclosed