Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8613273 | 0.99 | CCR6 (0.33) | CCR6CTSVCTSLCTSBCTSS | |
| SCHEMBL8025500 | 0.78 | CCR6 (0.33) | CCR6 | |
| SCHEMBL8021901 | 0.78 | CTSL (0.33) | CCR6CTSLCTSBCTSK | |
| Hydrochloric Acid SCHEMBL8613644 | 0.77 | CCR6 (0.35) | CCR6 | |
| Hydrochloric Acid SCHEMBL8611960 | 0.76 | MITF (0.32) | CCR6 | |
| SCHEMBL4665306 | 0.75 | OPRM1 (0.45) | CTSLCTSBCTSK | |
| SCHEMBL28557796 | 0.73 | ATM (0.35) | CCR6 | |
| SCHEMBL8009453 | 0.71 | SLC6A4 (0.42) | CCR6 | |
| SCHEMBL13899831 | 0.71 | — | — | |
| SCHEMBL5199186 | 0.71 | TLR4 (0.41) | CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |