Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899831 | 0.81 | — | — | |
| SCHEMBL9190051 | 0.78 | TLR4 (0.44) | TLR4MT-CO2ALOX5 | |
| SCHEMBL6652483 | 0.77 | CCR6 (0.34) | CCR6METAP1MITFHSP90AA1ADRA2A | |
| SCHEMBL6907551 | 0.76 | TLR4 (0.47) | TLR4MT-CO2ALOX5 | |
| SCHEMBL8019882 | 0.74 | SIGMAR1 (0.35) | TLR4CCR6METAP1MITFHSP90AA1 | |
| SCHEMBL4631245 | 0.74 | HTR6 (0.39) | CCR6METAP1MITFHSP90AA1 | |
| SCHEMBL6865770 | 0.74 | HTR6 (0.39) | CCR6METAP1MITFHSP90AA1 | |
| Hydrochloric Acid SCHEMBL8615192 | 0.73 | CCR6 (0.35) | TLR4CCR6METAP1MITFHSP90AA1 | |
| SCHEMBL6865388 | 0.72 | CA1 (0.45) | CCR6 | |
| SCHEMBL3146259 | 0.72 | CA1 (0.45) | CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411110-B1 | Spiro compounds as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-08-22 | — | — | EP | disclosed |
| US-7256170-B2 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2007-08-14 | — | — | US | disclosed |
| EP-1411110-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | SORD, PIR, AKR1C4 | TLR4 1520/4885CCR6 772/4885METAP1 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.