Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019625 | 0.98 | SHBG (0.41) | SHBGCYP1A2ATMMETAP2CTSK | |
| SCHEMBL8019782 | 0.95 | — | — | |
| SCHEMBL8020391 | 0.90 | — | — | |
| SCHEMBL28930071 | 0.75 | SHBG (0.42) | SHBGCYP1A2ATMNOS1NOS2 | |
| SCHEMBL1524656 | 0.74 | NOS1 (0.47) | SHBGCYP1A2ATMNOS1NOS2 | |
| SCHEMBL8020431 | 0.74 | — | — | |
| SCHEMBL9819745 | 0.72 | CTSK (0.40) | CYP1A2CTSK | |
| SCHEMBL16411251 | 0.72 | SHBG (0.39) | SHBGCYP1A2ATMNOS1NOS2 | |
| SCHEMBL8020386 | 0.72 | CTSK (0.40) | CYP1A2CTSK | |
| SCHEMBL16892514 | 0.72 | SHBG (0.44) | SHBGCYP1A2ATMNOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971904-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042682-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |