Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852338 | 0.86 | P2RX7 (0.44) | P2RX7L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL28779579 | 0.83 | KMT2A (0.44) | P2RX7L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL11683733 | 0.83 | P2RX7 (0.45) | P2RX7L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL7806397 | 0.81 | KDM4E (0.50) | P2RX7L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL13458380 | 0.80 | KDM4E (0.51) | P2RX7LMNAMKNK1MKNK2TDP1 | |
| SCHEMBL11330373 | 0.80 | P2RX7 (0.43) | P2RX7L3MBTL1LMNAMKNK1MKNK2 | |
| SCHEMBL7626781 | 0.79 | MKNK1 (0.46) | P2RX7LMNAMKNK1MKNK2CHRNB2 | |
| SCHEMBL28018480 | 0.79 | POLM (0.52) | LMNA | |
| SCHEMBL7005171 | 0.76 | P2RX7 (0.47) | P2RX7LMNASMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL7816179 | 0.75 | P2RX7 (0.54) | P2RX7L3MBTL1LMNAMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876344-B1 | PYRIDYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR PRODUCING THEM AND AGENTS CONTAINING THEM | BASF AG (DE) | 2000-08-23 | — | — | EP | claimed |
| US-6043197-A | PESTICIDES, FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |
| US-5965587-A | PESTICIDES, FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |