Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458380 | 0.85 | KDM4E (0.51) | P2RX7MKNK1MKNK2LMNAKDM4E | |
| SCHEMBL7626781 | 0.83 | MKNK1 (0.46) | P2RX7SSTR4MKNK1MKNK2CHRNB2 | |
| SCHEMBL7806397 | 0.81 | KDM4E (0.50) | P2RX7SSTR4MKNK1MKNK2CHRNB2 | |
| SCHEMBL8020420 | 0.80 | P2RX7 (0.44) | P2RX7SSTR4MKNK1MKNK2CHRNB2 | |
| SCHEMBL29852338 | 0.80 | P2RX7 (0.44) | P2RX7SSTR4CHRNB2CHRNA4LMNA | |
| SCHEMBL7816179 | 0.79 | P2RX7 (0.54) | P2RX7SSTR4MKNK1MKNK2CHRNB2 | |
| SCHEMBL11683733 | 0.78 | P2RX7 (0.45) | P2RX7SSTR4CHRNB2CHRNA4HTR2C | |
| SCHEMBL28779579 | 0.78 | KMT2A (0.44) | P2RX7SSTR4CHRNB2CHRNA4LMNA | |
| SCHEMBL6545410 | 0.74 | ADORA2A (0.50) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL9965997 | 0.74 | L3MBTL1 (0.56) | P2RX7CHRNB2CHRNA4KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023207942-A1 | NUCLEOSIDE DRUG FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF | 北京沐华生物科技有限责任公司 | 2023-11-02 | — | — | WO | claimed |
| EP-0000745-B1 | SALT OF AN OPTICALLY ACTIVE ISOMER OF PHENYLGLYCINE AND AN OPTICALLY ACTIVE ISOMER OF 2-AMINO BUTANOL AND PROCESS FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-15 | — | — | EP | claimed |
| EP-0000745-B1 | SALT OF AN OPTICALLY ACTIVE ISOMER OF PHENYLGLYCINE AND AN OPTICALLY ACTIVE ISOMER OF 2-AMINO BUTANOL AND PROCESS FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4182899-A | Optical resolution of amino acids into optical antipodes | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |
| EP-0000745-A1 | Salt of an optically active isomer of phenylglycine and an optically active isomer of 2-amino butanol and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-21 | — | — | EP | disclosed |