Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639870 | 0.82 | KDM4E (0.50) | KDM4EHPGDHSD17B10GFERL3MBTL1 | |
| SCHEMBL13458380 | 0.81 | KDM4E (0.51) | KDM4EHPGDHSD17B10P2RX7LMNA | |
| SCHEMBL11330373 | 0.81 | P2RX7 (0.43) | KDM4EP2RX7GFERSSTR4HTR2C | |
| SCHEMBL11683733 | 0.81 | P2RX7 (0.45) | KDM4EP2RX7SSTR4HTR2CL3MBTL1 | |
| SCHEMBL29852338 | 0.81 | P2RX7 (0.44) | P2RX7SSTR4L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL8020420 | 0.81 | P2RX7 (0.44) | P2RX7SSTR4L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL7626781 | 0.80 | MKNK1 (0.46) | P2RX7SSTR4HTR2CMEN1KMT2A | |
| SCHEMBL6384911 | 0.79 | KDM4E (0.47) | KDM4EHPGDHSD17B10GFERL3MBTL1 | |
| SCHEMBL7816179 | 0.79 | P2RX7 (0.54) | KDM4EP2RX7GFERSSTR4HTR2C | |
| SCHEMBL7364217 | 0.78 | L3MBTL1 (0.62) | KDM4EL3MBTL1MEN1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117650-A2 | USE OF SUBSTITUTED 5-HYDROXYPYRAZOLES, NOVEL 5-HYDROXYPYRAZOLES, METHODS FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020399-A2 | USE OF SUBSTITUTED 5-HYDROXYPYRAZOLES, NOVEL 5-HYDROXYPYRAZOLES, METHODS FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |