Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626781 | 0.81 | MKNK1 (0.46) | P2RX7MKNK1MKNK2SSTR4HTR2C | |
| SCHEMBL7806397 | 0.79 | KDM4E (0.50) | P2RX7MKNK1MKNK2SSTR4KDM4E | |
| SCHEMBL11330373 | 0.79 | P2RX7 (0.43) | P2RX7MKNK1MKNK2SSTR4KDM4E | |
| SCHEMBL13458380 | 0.79 | KDM4E (0.51) | P2RX7MKNK1MKNK2ALDH1A1KDM4E | |
| SCHEMBL15516810 | 0.78 | MAPT (0.65) | P2RX7MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL28131091 | 0.78 | HSP90AA1 (0.68) | MAPTHSP90AA1ALDH1A1KDM4ELMNA | |
| SCHEMBL7195412 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ECTSD | |
| SCHEMBL11683733 | 0.75 | P2RX7 (0.45) | P2RX7SSTR4ALDH1A1KDM4EHTR2C | |
| SCHEMBL29852338 | 0.75 | P2RX7 (0.44) | P2RX7SSTR4LMNAL3MBTL1CHRNB2 | |
| SCHEMBL8020420 | 0.75 | P2RX7 (0.44) | P2RX7MKNK1MKNK2SSTR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117650-A2 | USE OF SUBSTITUTED 5-HYDROXYPYRAZOLES, NOVEL 5-HYDROXYPYRAZOLES, METHODS FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020399-A2 | USE OF SUBSTITUTED 5-HYDROXYPYRAZOLES, NOVEL 5-HYDROXYPYRAZOLES, METHODS FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |