Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030542 | 0.93 | CASR (0.41) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL8036249 | 0.93 | NR1H4 (0.41) | NR1H4NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8030312 | 0.90 | NR1H4 (0.34) | NR1H4NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL8030746 | 0.89 | KMT2A (0.33) | NPC1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL8030749 | 0.88 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL8030189 | 0.88 | BDKRB2 (0.39) | NPC1RAB9ASMN1; SMN2MITFPAX8 | |
| SCHEMBL8030220 | 0.84 | NR1H4 (0.45) | NR1H4NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8029956 | 0.83 | MLYCD (0.37) | NR1H4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8036105 | 0.82 | MLYCD (0.36) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8020608 | 0.82 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2MITFPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |