SCHEMBL8020629

SCHEMBL8020629

O=C(O)CC(Cl)c1cc(N2C(=O)c3ccccc3C2=O)c(F)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
NFKB1 P19838 2/20 0.39
PMP22 Q01453 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
GRM1 Q13255 4/20 0.38
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
CTSA P10619 1/20 0.36
GRM4 Q14833 4/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
GLA P06280 1/20 0.36
POLB P06746 1/20 0.36
CYP2D6 P10635 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7734095 0.76 ALDH1A1 (0.39) CYP3A4NFKB1PMP22MEN1KMT2A
SCHEMBL7734263 0.74 CYP3A4 (0.39) CYP3A4NFKB1PMP22MEN1KMT2A
SCHEMBL30566764 0.74 ESR1 (0.49) CYP3A4NFKB1PMP22MEN1KMT2A
SCHEMBL5388823 0.74 ESR1 (0.49) CYP3A4NFKB1PMP22MEN1KMT2A
SCHEMBL7729097 0.71 CYP3A4 (0.56) CYP3A4NFKB1PMP22MEN1KMT2A
SCHEMBL8082773 0.71 GRM1 (0.43) CYP3A4NFKB1PMP22GRM1GRM4
SCHEMBL8082768 0.71 GRM1 (0.43) CYP3A4NFKB1PMP22GRM1GRM4
SCHEMBL7729709 0.70 GRM1 (0.39) MEN1KMT2AGRM1GRM4TP53
SCHEMBL7729726 0.70 PPOX (0.42) MEN1KMT2AGRM1GRM4TP53
SCHEMBL30566773 0.70 NPC1 (0.55) MEN1KMT2AALDH1A1GLAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000086631-A PHTHALIMIDE COMPOUND, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT MITSUBISHI CHEMICALS CORP 2000-03-28 JP disclosed