Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4618681 | 0.86 | CES1 (0.58) | MAPTKMT2ACES1TSHRHSD17B10 | |
| SCHEMBL8600048 | 0.83 | CES1 (0.47) | MAPTKMT2ACES1TSHRHSD17B10 | |
| SCHEMBL819138 | 0.82 | CES1 (0.54) | MAPTKMT2ACES1TSHRHSD17B10 | |
| SCHEMBL27571079 | 0.81 | CA2 (0.50) | MAPTKMT2ACES1TDP1ALDH1A1 | |
| SCHEMBL12913259 | 0.80 | CES1 (0.52) | MAPTCES1TSHRHSD17B10TDP1 | |
| SCHEMBL28304793 | 0.80 | CES1 (0.52) | MAPTCES1TSHRHSD17B10TDP1 | |
| SCHEMBL11011559 | 0.78 | CES1 (0.50) | MAPTKMT2ACES1TSHRHSD17B10 | |
| SCHEMBL7039215 | 0.78 | MAPT (0.57) | MAPTKMT2ACES1TSHRHSD17B10 | |
| SCHEMBL28192063 | 0.77 | LMNA (0.61) | TDP1POLBCYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL9632467 | 0.77 | CES1 (0.54) | MAPTKMT2ACES1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093323-B | Beta-functionalized chiral homoallylic alcohol derivative and preparation method and application thereof | 武汉大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-114057666-B | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-115093323-A | Beta-functionalized chiral homoallyl alcohol derivative and preparation method and application thereof | 武汉大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-114989035-A | Sulfuryl fluoride promoted reaction method for converting beta-diketone to alkyne | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | disclosed |
| CN-114057666-A | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-107548397-B | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-107548396-B | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-106478443-B | The method that difluoro Ya Jia Ji Phosphonium inner salts are used to synthesize β keto-amides as new ammonolysis reagent | 四川理工学院 | 2018-04-03 | — | — | CN | disclosed |
| CN-107548396-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107548397-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-106478443-A | The method that difluoro methylene inner salt is used for synthesizing β keto-amide as new ammonolysis reagent | 四川理工学院 | 2017-03-08 | — | — | CN | disclosed |
| CN-102321066-B | Method for producing aryl-aminopropanols | SALTIGO GMBH | 2014-07-23 | — | — | CN | disclosed |
| CN-1445224-B | Process for preparing arylaminopropanols | SALTIGO GMBH | 2012-07-11 | — | — | CN | disclosed |
| CN-102321066-A | The method for preparing the arylamino propyl alcohol | SALTIGO GMBH | 2012-01-18 | — | — | CN | disclosed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | disclosed |
| EP-0973856-A1 | N-ACYL OXAZIRIDINES AS BLEACH AGENTS | UNILEVER N.V. (NL) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998045397-A1 | N-ACYL OXAZIRIDINES AS BLEACH AGENTS | UNILEVER N.V. (NL) | 1998-10-15 | — | — | WO | disclosed |
| US-5755991-A | USEFUL IN CLEANING FABRICS, HOUSEHOLD FIXTURES, TABLEWARE AND DENTURES | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1998-05-26 | — | — | US | disclosed |