Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586652 | 0.98 | NUDT1 (0.67) | NUDT1BACE1TRPA1HSP90AA1DRD2 | |
| SCHEMBL15026744 | 0.96 | BACE1 (0.59) | NUDT1BACE1TRPA1HSP90AA1DRD2 | |
| SCHEMBL12881779 | 0.86 | NUDT1 (0.69) | NUDT1BACE1HSP90AA1DRD2DRD1 | |
| SCHEMBL917277 | 0.85 | NUDT1 (0.72) | NUDT1BACE1HSP90AA1DRD2DRD1 | |
| SCHEMBL15054138 | 0.84 | NUDT1 (0.50) | NUDT1BACE1TRPA1HSP90AA1DRD2 | |
| SCHEMBL10597858 | 0.84 | BACE1 (0.81) | NUDT1BACE1HSP90AA1DRD2DRD1 | |
| SCHEMBL7182409 | 0.84 | NUDT1 (0.71) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL11596345 | 0.83 | NUDT1 (0.66) | NUDT1BACE1HSP90AA1CNR1CNR2 | |
| SCHEMBL5682327 | 0.82 | NUDT1 (0.68) | NUDT1BACE1HSP90AA1THRBCNR1 | |
| SCHEMBL27749308 | 0.82 | NUDT1 (0.69) | NUDT1BACE1HSP90AA1DRD2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
| EP-2300484-B1 | NOVEL CLASS OF SPIRO PIPERIDINES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | PFIZER (US) | 2011-12-14 | — | — | EP | disclosed |
| EP-0984912-A1 | METHOD FOR CONTINUOUS PRODUCTION OF DIHYDROXYDIPHENYLALKANES | Bayer Aktiengesellschaft (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998052896-A1 | METHOD FOR CONTINUOUS PRODUCTION OF DIHYDROXYDIPHENYLALKANES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |
| US-4115355-A | SUBSTITUTED PHENOLS | NIPPON ZEON CO. LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | SULT2A1, SULT1A1, SULT1E1 | NUDT1 576/4885BACE1 2145/4885TRPA1 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.