Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.58 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025278 | 0.81 | GRM5 (0.59) | MEN1NPC1PKMRAB9AKMT2A | |
| SCHEMBL29127266 | 0.77 | TDP1 (0.50) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL15337002 | 0.74 | KMO (1.00) | KMOTSHRKDM4EMEN1NPC1 | |
| SCHEMBL21974233 | 0.74 | KMO (1.00) | KMOTSHRKDM4EMEN1NPC1 | |
| SCHEMBL31060580 | 0.74 | KMO (1.00) | KMOTSHRKDM4EMEN1NPC1 | |
| SCHEMBL4753610 | 0.74 | KMO (1.00) | KMOTSHRKDM4EMEN1NPC1 | |
| SCHEMBL5310798 | 0.74 | KMO (1.00) | KMOTSHRKDM4EMEN1NPC1 | |
| SCHEMBL6823764 | 0.74 | TAS1R3 (0.56) | TAS1R3TAS1R2TSHRKDM4EMEN1 | |
| SCHEMBL9699898 | 0.74 | TAS1R3 (0.71) | TAS1R3TAS1R2KMT2AF10SSTR3 | |
| SCHEMBL3366745 | 0.74 | TAS1R3 (0.71) | TAS1R3TAS1R2KMT2AF10SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |