Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 10/20 | 0.35 |
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022291 | 0.86 | HIF1A (0.37) | HIF1ATSHRPPARGPPARAHSD17B2 | |
| SCHEMBL8500992 | 0.78 | HIF1A (0.42) | HIF1AHSD17B2KDM4EALDH1A1MAPT | |
| SCHEMBL8500990 | 0.78 | HIF1A (0.42) | HIF1AHSD17B2KDM4EALDH1A1MAPT | |
| SCHEMBL8500995 | 0.78 | HIF1A (0.43) | HIF1AHSD17B2KDM4EALDH1A1MAPT | |
| SCHEMBL8026232 | 0.71 | HIF1A (0.39) | HIF1AHSD17B2KDM4EALDH1A1MAPT | |
| SCHEMBL8020434 | 0.70 | PPARG (0.47) | HIF1APPARGPPARANPC1 | |
| SCHEMBL8020436 | 0.69 | PPARG (0.48) | HIF1APPARGPPARANPC1 | |
| SCHEMBL8020917 | 0.68 | MAPT (0.37) | HIF1AHSD17B2KDM4EALDH1A1MAPT | |
| SCHEMBL8022508 | 0.68 | MAPT (0.37) | HIF1AHSD17B2KDM4EALDH1A1MAPT | |
| SCHEMBL8020470 | 0.68 | L3MBTL1 (0.40) | TSHRHSD17B2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |