Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023149 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| SCHEMBL8017497 | 0.68 | CYP1A2 (0.34) | ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8006370 | 0.68 | ALDH1A1 (0.32) | ALDH1A1MAPK1 | |
| SCHEMBL8014938 | 0.64 | KIF11 (0.36) | ALDH1A1 | |
| SCHEMBL15557229 | 0.64 | GAA (0.32) | GAA | |
| SCHEMBL8005753 | 0.61 | KIF11 (0.36) | ALDH1A1 | |
| SCHEMBL4808079 | 0.61 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL31497105 | 0.60 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNAMAPK1MAPT | |
| Biphenyl SCHEMBL9403462 | 0.60 | ALDH1A1 (0.84) | ALDH1A1TDP1LMNACRHBPCRHR2 | |
| Biphenyl SCHEMBL9576411 | 0.60 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |