Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020026 | 0.88 | BACE1 (0.38) | MEN1KMT2ABACE1GAAALDH1A1 | |
| SCHEMBL8018669 | 0.88 | OPRM1 (0.38) | MEN1KMT2ABACE1GAAKCNK3 | |
| SCHEMBL27512364 | 0.79 | OPRM1 (0.36) | MEN1KMT2ABACE1GAAALDH1A1 | |
| SCHEMBL27512707 | 0.79 | BACE1 (0.37) | MEN1KMT2ABACE1ALDH1A1CPB2 | |
| SCHEMBL8025163 | 0.72 | SIRT2 (0.40) | MEN1KMT2ASTSGAANPSR1 | |
| SCHEMBL8018813 | 0.70 | NPSR1 (0.42) | MEN1KMT2ANPSR1KCNK3KCNK9 | |
| SCHEMBL8025166 | 0.67 | GAA (0.42) | MEN1KMT2AGAAABCB1ALDH1A1 | |
| SCHEMBL29254982 | 0.67 | MAPK1 (0.33) | — | |
| SCHEMBL8018811 | 0.67 | NPSR1 (0.43) | MEN1KMT2ASTSGAANPSR1 | |
| SCHEMBL499531 | 0.66 | ERCC5 (0.43) | MEN1KMT2AGAAALDH1A1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |