Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512364 | 0.91 | OPRM1 (0.36) | OPRM1OPRL1MEN1KMT2ABACE1 | |
| SCHEMBL8020026 | 0.88 | BACE1 (0.38) | MEN1KMT2ABACE1ALDH1A1GAA | |
| SCHEMBL8022577 | 0.88 | MEN1 (0.38) | MEN1KMT2ABACE1KCNK3ALDH1A1 | |
| SCHEMBL27512707 | 0.79 | BACE1 (0.37) | MEN1KMT2ABACE1ALDH1A1LMNA | |
| SCHEMBL8018983 | 0.72 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1KCNK3ALDH1A1 | |
| SCHEMBL8007797 | 0.70 | CES2 (0.42) | OPRM1OPRL1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8018985 | 0.67 | OPRM1 (0.39) | OPRM1OPRL1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29254982 | 0.67 | MAPK1 (0.33) | — | |
| SCHEMBL8007793 | 0.67 | CES2 (0.44) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL6050410 | 0.66 | CTNNB1 (0.42) | MEN1KMT2AKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |