Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018895 | 0.86 | MEN1 (0.36) | GAAALDH1A1HPGDHTTMEN1 | |
| SCHEMBL8018985 | 0.86 | OPRM1 (0.39) | GAAGRM5ALDH1A1HTTMEN1 | |
| SCHEMBL8025266 | 0.83 | TAS1R3 (0.37) | MEN1KMT2ARAB9ACHRNA1CHRNG | |
| SCHEMBL8018811 | 0.73 | NPSR1 (0.43) | GAAGRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL28714346 | 0.68 | PARP1 (0.52) | GAAALDH1A1HPGDKDM4EHTT | |
| SCHEMBL8022577 | 0.67 | MEN1 (0.38) | GAAALDH1A1MEN1KMT2AABCB1 | |
| SCHEMBL16506712 | 0.66 | KMO (0.64) | GAAGRM5ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL8008231 | 0.66 | KMO (0.64) | GAAGRM5ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL499531 | 0.65 | ERCC5 (0.43) | GAAALDH1A1HPGDKDM4EHTT | |
| SCHEMBL7673703 | 0.65 | MEN1 (0.46) | GAAALDH1A1HPGDHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |