SCHEMBL8022609

SCHEMBL8022609

O=C([SiH2]O[SiH2]Oc1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.39
TSHR P16473 4/20 0.39
HSD17B10 Q99714 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
PARP1 P09874 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.38
AKR1C3 P42330 1/20 0.38
F2 P00734 1/20 0.38
LMNA P02545 1/20 0.38
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
DAO P14920 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715684 0.75 LTA4H (0.45) TSHRHSD17B10TDP1MAPTRECQL
SCHEMBL707758 0.70 LTA4H (0.50) TSHRHSD17B10TDP1MAPTRECQL
Hydrochloric Acid SCHEMBL9709369 0.67 LTA4H (0.47) TSHRHSD17B10TDP1MAPTRECQL
SCHEMBL12584707 0.65 TDP1 (0.57) TSHRHSD17B10TDP1POLBCYP3A4
Biphenyl SCHEMBL2499426 0.64 ALDH1A1 (0.50) TSHRHSD17B10TDP1CYP3A4CYP2C19
SCHEMBL10612831 0.63 LTA4H (0.38) TSHRTDP1CYP2C19L3MBTL1LMNA
SCHEMBL3464324 0.62 LTA4H (0.41) TSHRTDP1RECQLL3MBTL1ALDH1A1
SCHEMBL28957090 0.62 TDP1 (0.52) TSHRHSD17B10TDP1POLBCYP3A4
Diphenylether SCHEMBL3013964 0.61 PARP10 (0.88) PARP10TSHRHSD17B10TDP1POLB
SCHEMBL8731695 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4020226-A CARBON FIBER IMPREGNATED WITH BARIUM SULFATE, HEXAMETHYLENETETRAMINE AND POLYOXYPHENYL METHANE-PHENOXY-SILOXANE ANDRIANOV KUZMA A 1977-04-26 US claimed
EP-0699728-B1 BINDER COMPOSITION FOR FRICTION MATERIALS, AND FRICTION MATERIAL OSAKA GAS CO LTD (JP) 2000-01-19 EP disclosed
US-4020226-A CARBON FIBER IMPREGNATED WITH BARIUM SULFATE, HEXAMETHYLENETETRAMINE AND POLYOXYPHENYL METHANE-PHENOXY-SILOXANE ANDRIANOV KUZMA A 1977-04-26 US disclosed
US-4020226-A CARBON FIBER IMPREGNATED WITH BARIUM SULFATE, HEXAMETHYLENETETRAMINE AND POLYOXYPHENYL METHANE-PHENOXY-SILOXANE ANDRIANOV KUZMA A 1977-04-26 US disclosed