SCHEMBL707758

SCHEMBL707758

c1ccc(O[SiH2]Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.50
TSHR P16473 1/20 0.50
CA4 P22748 1/20 0.45
KCNA3 P22001 1/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
LMNA P02545 1/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA7 P43166 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
SRC P12931 1/20 0.36
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9709369 0.97 LTA4H (0.47) LTA4HTSHRCA4KCNA3CA5A
Naphthalene SCHEMBL28994860 0.91 CYP2A6 (0.44) LTA4HTSHRCA4KCNA3CA5A
Biphenyl SCHEMBL2499426 0.91 ALDH1A1 (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL9715684 0.88 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
Butadiene SCHEMBL3336285 0.87 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A
Butane SCHEMBL2501351 0.87 LTA4H (0.43) LTA4HTSHRCA4KCNA3LMNA
SCHEMBL10612831 0.84 LTA4H (0.38) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL2115587 0.83 CA4 (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL3464324 0.83 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A
Biphenyl SCHEMBL5635143 0.79 RAB9A (0.40) LTA4HTSHRLMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150249007-A1 Methods to Prepare Silicon-Containing Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US claimed
EP-2864381-A1 PROCESS FOR PRODUCING A COMPOSITE MATERIAL BASF SE (DE) 2015-04-29 EP claimed
US-8865858-B2 Process for producing a composite material BASF SE (DE) 2014-10-21 US claimed
WO-2014001273-A1 PROCESS FOR PRODUCING A COMPOSITE MATERIAL BASF SE (DE) 2014-01-03 WO claimed
US-20130345385-A1 PROCESS FOR PRODUCING A COMPOSITE MATERIAL BASF SE (DE) 2013-12-26 US claimed
US-8337743-B2 Process for producing a polyethylene-polypropylene multilayer blown film TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2012-12-25 US claimed
US-20110215445-A1 Methods to Prepare Silicon-Containing Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-09-08 US claimed
EP-2363512-A1 Methods to prepare silicon-containing films AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-09-07 EP claimed
US-20100297459-A1 Process for Producing a Polyethylene-Polypropylene Multilayer Blown Film TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-11-25 US claimed
JP-2010530323-A 2010-09-09 JP claimed
EP-2216367-A1 High impact resistance polyethylene Total Petrochemicals Research Feluy (BE) 2010-08-11 EP claimed
EP-2160282-A1 PROCESS FOR PRODUCING A POLYETHYLENE-POLYPROPYLENE MULTILAYER BLOWN FILM Total Petrochemicals Research Feluy (BE) 2010-03-10 EP claimed
US-20100035035-A1 High Clarity Easy Tear Multilayer Films TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-02-11 US claimed
EP-2075125-A1 Corona treated polyethylene films TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-07-01 EP claimed
WO-2009077622-A2 CORONA TREATED POLYETHYLENE FILMS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-06-25 WO claimed
WO-2009000783-A1 PROCESS FOR PRODUCING A POLYETHYLENE-POLYPROPYLENE MULTILAYER BLOWN FILM TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2008-12-31 WO claimed
EP-2006070-A1 Process for producing a polyethylene-polypropylene multilayer blown film TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2008-12-24 EP claimed
EP-1890876-A1 HIGH CLARITY EASY TEAR MULTILAYER FILMS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2008-02-27 EP claimed
WO-2006134155-A1 HIGH CLARITY EASY TEAR MULTILAYER FILMS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2006-12-21 WO claimed
EP-1733873-A1 High clarity easy tear multilayer films TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2006-12-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110215445-A1 Methods to Prepare Silicon-Containing Films FHIT, CD99, CA1 LTA4H 3976/4885TSHR 4561/4885CA4 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.