SCHEMBL3464324

SCHEMBL3464324

[SiH3]O[SiH2]Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
TSHR P16473 1/20 0.41
CA4 P22748 1/20 0.38
KCNA3 P22001 1/20 0.35
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
LMNA P02545 1/20 0.32
NR1H2 P55055 1/20 0.32
BAX Q07812 1/20 0.32
MAOA P21397 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RECQL P46063 1/20 0.31
SRC P12931 1/20 0.31
CA7 P43166 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707758 0.83 LTA4H (0.50) LTA4HTSHRCA4KCNA3CA5A
Hydrochloric Acid SCHEMBL9709369 0.80 LTA4H (0.47) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL9715684 0.78 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
Biphenyl SCHEMBL2499426 0.76 ALDH1A1 (0.50) LTA4HTSHRCA4KCNA3CA5A
Naphthalene SCHEMBL28994860 0.76 CYP2A6 (0.44) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL2115587 0.74 CA4 (0.50) LTA4HTSHRCA4KCNA3CA5A
Butadiene SCHEMBL3336285 0.72 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A
Butane SCHEMBL2501351 0.72 LTA4H (0.43) LTA4HTSHRCA4KCNA3LMNA
SCHEMBL10612831 0.70 LTA4H (0.38) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL10568357 0.69 LMNA (0.42) LTA4HTSHRCA4KCNA3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010147227-A1 METHOD OF PRODUCING A POLYETHER-MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2010-12-23 WO disclosed
CN-1809764-A Antireflective film ASAHI CHEMICAL IND (JP) 2006-07-26 CN disclosed