SCHEMBL8022859

SCHEMBL8022859

Cc1c(C(=O)Cl)ccc(S(C)(=O)=O)c1-c1ccon1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.37
MDM2 Q00987 1/20 0.34
P2RX3 P56373 1/20 0.33
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4701584 0.88 GAA (0.38) GAAMDM2P2RX3KDM4EMEN1
SCHEMBL4697806 0.85 GAA (0.48) GAAMDM2P2RX3KDM4ELMNA
SCHEMBL8780086 0.79 LMNA (0.35) GAAMDM2P2RX3LMNA
SCHEMBL28927865 0.77 P2RX3 (0.33) GAAP2RX3
SCHEMBL8175098 0.76 GAA (0.42) GAAP2RX3KDM4EMAPTKMT2A
SCHEMBL6587396 0.75 KDM4E (0.40) KDM4EMEN1LMNAMAPTKMT2A
SCHEMBL8027214 0.75 SMN1; SMN2 (0.33) GAALMNA
SCHEMBL5638807 0.74 L3MBTL1 (0.38) LMNA
SCHEMBL9761613 0.73 ALDH1A1 (0.38) LMNAMAPT
SCHEMBL30608210 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6147031-A Benzoylpyrazole compounds, intermediate preparing therefor and herbicides NIPPON SODA CO., LTD. (JP) 2000-11-14 US disclosed
EP-1031573-A1 NOVEL BENZOYLPYRAZOLE COMPOUNDS, INTERMEDIATES, AND HERBICIDES NIPPON SODA CO., LTD. (JP) 2000-08-30 EP disclosed