Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 8/20 | 0.55 |
| ▸ | CA1 | P00915 | 7/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746782 | 0.90 | LMNA (0.70) | SNCALMNAALDH1A1CYP3A4HPGD | |
| SCHEMBL11540311 | 0.86 | SNCA (0.58) | SNCALMNAALDH1A1CYP3A4HPGD | |
| SCHEMBL8023015 | 0.85 | CA1 (0.67) | ALDH1A1HSD17B10MEN1KMT2ANSD2 | |
| SCHEMBL278412 | 0.83 | SNCA (1.00) | SNCALMNAALDH1A1CYP3A4HPGD | |
| SCHEMBL29843770 | 0.83 | SNCA (1.00) | SNCALMNAALDH1A1CYP3A4HPGD | |
| SCHEMBL29668447 | 0.83 | SNCA (1.00) | SNCALMNAALDH1A1CYP3A4HPGD | |
| SCHEMBL29757686 | 0.83 | SNCA (0.71) | SNCALMNAALDH1A1CYP3A4HPGD | |
| SCHEMBL11961726 | 0.81 | ALDH1A1 (0.91) | SNCALMNAALDH1A1CYP3A4HPGD | |
| SCHEMBL193716 | 0.79 | LMNA (1.00) | LMNAMEN1KMT2ACA2CA1 | |
| SCHEMBL9839080 | 0.79 | LMNA (0.82) | LMNAALDH1A1MEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10967096-B2 | Tissue sealant compositions, vascular closure devices, and uses thereof | MEDIBEACON INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-10960104-B2 | Tissue sealant compositions, vascular closure devices, and uses thereof | MEDIBEACON INC. (US) | 2021-03-30 | — | — | US | disclosed |
| US-10881759-B2 | Tissue sealant compositions, vascular closure devices, and uses thereof | MEDIBEACON INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20190192727-A1 | TISSUE SEALANT COMPOSITIONS, VASCULAR CLOSURE DEVICES, AND USES THEREOF | MALLINCKRODT INC. | 2019-06-27 | — | — | US | disclosed |
| US-20190192728-A1 | TISSUE SEALANT COMPOSITIONS, VASCULAR CLOSURE DEVICES, AND USES THEREOF | MALLINCKRODT INC. | 2019-06-27 | — | — | US | disclosed |
| US-20160331862-A1 | TISSUE SEALANT COMPOSITIONS, VASCULAR CLOSURE DEVICES, AND USES THEREOF | MALLINCKRODT INC. | 2016-11-17 | — | — | US | disclosed |
| US-9433700-B2 | Tissue sealant compositions, vascular closure devices, and uses thereof | MEDIBEACON INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-20120041479-A1 | Tissue Sealant Compositions, Vascular Closure Devices, and Uses Thereof | MEDIBEACON, INC. | 2012-02-16 | — | — | US | disclosed |
| WO-2010129258-A2 | TISSUE SEALANT COMPOSITIONS, VASCULAR CLOSURE DEVICES, AND USES THEREOF | MALLINCKRODT INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-7297495-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-6951930-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-20030113765-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2003-06-19 | — | — | US | disclosed |
| US-6472153-B1 | COVALENTLY BOUND OLIGONUCLEOTIDE/MINOR GROOVE BINDER/LATENT FLUOROPHORE COMBINATION | EPOCH BIOSCIENCES, INC. | 2002-10-29 | — | — | US | disclosed |
| EP-1224332-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | Epoch Biosciences, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001031063-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | EPOCH BIOSCIENCES, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | DDX21, RNGTT, NOP2 | SNCA 3959/4885LMNA 347/4885ALDH1A1 3480/4885 |
| US-20030113765-A1 | Hybridization-triggered fluorescent detection of nucleic acids | DDX21, RNGTT, NOP2 | SNCA 3959/4885LMNA 347/4885ALDH1A1 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.