Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998742 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1HIF1ATSHRCYP3A4 | |
| SCHEMBL12066584 | 0.77 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL9998739 | 0.76 | CA1 (0.50) | TDP1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL2085361 | 0.75 | ALDH1A1 (0.59) | TDP1ALDH1A1HIF1ATSHRCYP3A4 | |
| SCHEMBL6203515 | 0.74 | ALDH1A1 (0.68) | TDP1ALDH1A1HIF1ATSHRCYP3A4 | |
| SCHEMBL9998848 | 0.74 | ALDH1A1 (0.31) | TDP1ALDH1A1HIF1ATSHRCYP3A4 | |
| SCHEMBL28252592 | 0.74 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL29379293 | 0.74 | TSHR (0.56) | TDP1ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL9998849 | 0.74 | TSHR (0.56) | TDP1ALDH1A1TSHRCYP3A4RECQL | |
| SCHEMBL22556946 | 0.74 | GPR35 (0.59) | TDP1ALDH1A1HIF1ATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738713-B1 | Process for the preparation of pesticidal 1-(chloroaryl)heterocyclic compounds | RHONE POULENC AGROCHIMIE (FR) | 2000-02-09 | — | — | EP | disclosed |
| US-5726324-A | 1-(nitroaryl)pyrrole intermediates to pesticidal 1-(haloaryl)pyrroles | RHONE-POULENC INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5631381-A | Process for the preparation of pesticidal 1-(haloaryl) heterocyclic compounds | RHONE-POULENC INC. (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0738713-A1 | Process for the preparation of pesticidal 1-(haloaryl)heterocyclic compounds | RHONE-POULENC AGROCHIMIE (FR) | 1996-10-23 | — | — | EP | disclosed |